Outcomes of Bilateral Cataract Surgery in Infants 7 to 24 Months of Age Using the Toddler Aphakia and Pseudophakia Treatment Study Registry

PurposeTo evaluate outcomes of bilateral cataract surgery in children aged 7 to 24 months and compare rates adverse events (AEs) with other Toddler Aphakia Pseudophakia Study (TAPS) registry outcomes.DesignRetrospective clinical study at 10 Infant Treatment (IATS) sites. Statistical analyses comparing this cohort previously reported TAPS cohorts.ParticipantsChildren enrolled the between 2004 2010.MethodsChildren underwent or without intraocular lens (IOL) placement age 5 years postsurgical follow-up.Main Outcome MeasuresVisual acuity (VA), occurrence strabismus, AEs, reoperations.ResultsA total 40 (76 eyes) who primary posterior capsulectomy were identified a median 11 (7–23); 68% received IOL. Recurrent visual axis opacification (VAO) occurred 7.5% was associated only use an IOL (odds ratio, 6.10; P = 0.005). Glaucoma suspect (GS) diagnosed 2.5%, but no child developed glaucoma. In cohort, AEs (8/40, 20%), including glaucoma GS VAO, reoperations similar proportion that published unilateral cohort. When analyzed 1 surgery, incidence correlated strongly (P 0.011/0.004) microcornea 0.040) not insertion 0.15).ConclusionsFollow-up after reveals low rate VAO very rare diagnosis compared infants cataracts operated < despite implantation most group months. The increases risk irrespective surgery. To outcomes. Retrospective cohorts. Children 2010. follow-up. Visual reoperations. A 0.15). Follow-up